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KMID : 0911820110120010021
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Korean Journal of Headache
2011 Volume.12 No. 1 p.21 ~ p.26
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Treatment of Headache with Botulinum Toxin
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Moon Heui-Soo
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Abstract
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Clinical data and experience to date have demonstrated that botulinum toxin is an effective and well-tolerated therapy
for several headaches, especially chronic migraine (CM). CM is a severely disabling condition and has been showed
to significantly reduce patients’ quality of life. Current treatment of CM may be complicated by the frequent use of acute
headache pain medications such as analgesics, triptans, or ergots. Botulinum toxin reduced headache and migraine days
and frequency of moderate to severe headache days with botulinum toxin, which in turn reduced the burden of illness
in patients with disabling CM. Further investigations will define the accurate pathophysiologic mechanisms of botulinum
toxin in the headache management. Further studies are needed in order to compare the efficacy of botulinum toxin with
other prophylactic drugs.
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KEYWORD
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Migraine, Botulinum toxin
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